(122) Lin,H., Fazzari,J., Linher-Melville,K., and Singh,G. High-throughput screening of compounds for targeting system Xc(-) in human breast cancer cells.[Abstract] Proceedings of the American Association for Cancer Research 2014; 2014: 5392. Poster presented at the American Association for Cancer Research Annual Meeting, April 5-9, 2014, San Diego, California.

 

(121) Habib,E., Linher-Melville,K., and Singh,G. H2O2 upregulates xCT in human breast cancer cells via NRF-2.[Abstract] Proceedings of the American Association for Cancer Research 2014; 2014: 506. Poster presented at the American Association for Cancer Research Annual Meeting, April 5-9, 2014, San Diego, California.

 

(120) Fazzari,J., Lin,H., Linher-Melville,K., and Singh,G. Targeting system xc- in breast cancer cells: Development of novel therapeutics.[Abstract]Proceedings of the American Association for Cancer Research 2014; 2014: 3233. Poster presented at the American Association for Cancer Research Annual Meeting, April 5-9, 2014, San Diego, California.

 

(119) Balenko,M.D., Seidlitz,E., and Singh,G. Analgesic effects of capsazepine on a mouse model of bone cancer pain.[Abstract] Proceedings of the American Association for Cancer Research 2014; 2014: 3687. Poster presented at the American Association for Cancer Research Annual Meeting, April 5-9, 2014, San Diego, California.

 

(118)   Zantinge,S.L., Linher-Melville,K., Sanli,T., and Singh,G. Prolactin plays a role in regulating fatty acid synthesis and metabolism in the prostate cancer cell line PC-3.[Abstract] Cancer Research 2012; 72: 5157. Poster presented at the American Association for Cancer Research Annual Meeting, March 31-April 4, 2012, Chicago, IL.

 

(117)   Storozhuk,Y., Sanli,T., Barron,C., Tsiani,E., Schultz,C., Farrell,T., Cutz,J.C., Bristow,R.G., Wright,J., Singh,G., and Tsakiridis,T. Metformin enhances radiation responses in non-small cell lung cancer.[Abstract] Radiotherapy and Oncology 2012;  S69. 26th Canadian Association of Radiation Oncology Annual Scientific Meeting.

 

(116)   Verschoor,M.L., Verschoor,C.P., and Singh,G. Role of Ets-1 in the regulation of energy metabolism in cancer cells.[Abstract] Cancer Research 2011; 70: 43. Poster presented at the American Association for Cancer Research Annual Meeting, April 17-21, 2010, Washington, DC.

 

(115)   Ungard,R., Seidlitz,E., De Ciantis,P., Yashpal,K., Henry,J.L., and Singh,G. Examination of the mechanism(s) of cancer-induced bone pain in animal models.[Abstract] Bone 2011; 48: S39. Poster presented at the 10th International Conference on Cancer-Induced Bone Disease, Sheffield, UK, September 22-25, 2010.

 

(114)   Tsakiridis,T., Storozhuk,Y., Toran,S., Hopmans,S., Cutz,J.C., Tsiani,E., Wright,J., and Singh,G. Metformin sensitizes human lung cancer xenografts to ionizing radiation: Response of the AMPK pathway.[Abstract] Cancer Research 2011; 71: 2491. Poster presented at the American Association for Cancer Research Annual Meeting, April 2-6, 2011, Orlando, FL.

 

(113)   Tsakiridis,T., Storozhuk,Y., Sanli,T., Linher-Melville,K., Hopmans,S., Cutz,J.C., Bristow,R.G., and Singh,G. Acute and chronic regulation of AMP-kinase (AMPK) by ionizing radiation and novel radiosensitizers: modulation of tumour cell cycle and survival.[Abstract] European Society of Radiation Therapy and Oncology 2011. Presented at the 12th International Wolfsberg Meeting 2011 on Molecular Radiation Biology / Oncology, Ermatingen, Switzerland.

 

(112)   Seidlitz,E.P., Sharma,M.K., and Singh,G. Glutamate release in bone metastasis.[Abstract] Bone 2011; 48: S32. Poster presented at the 10thInternational Conference on Cancer-Induced Bone Disease, Sheffield, UK, September 22-25, 2010.

 

(111)   Sanli,T., Linher,K., Tsakiridis,T., and Singh,G. Sestrins modulate the expression of the metabolic stress sensor AMPK in breast cancer cells.[Abstract]Cancer Research 2011; 71: 4071. Poster presented at the American Association for Cancer Research Annual Meeting, April 2-6, 2011, Orlando, FL.

 

(110)   Paschos,A., Laflamme,P., and Singh,G. The mitochondrial FAD-linked glycerol-3-phosphate dehydrogenase as an inhibitory target for cancer therapeutics.[Abstract] Cancer Research 2011; 70: 3694. Poster presented at the American Association for Cancer Research Annual Meeting, April 17-21, 2010, Washington, DC.

 

(109)   Paschos,A. and Singh,G. Oxidative stress as a target for drug development in prostate cancer.[Abstract] The Biological Chemistry of Inflammation as a Cause of Cancer 2011. A joint meeting between the AACR and the American Chemical Society - Chemistry in Cancer Research, January 30-February 2, 2011, San Diego, CA.

 

(108)   Linher,K. and Singh,G. Establishing a relationship between breast cancer, prolactin and altered fat metabolism.[Abstract] Cancer Research 2011; 70: 4-03. Poster presented at the American Association for Cancer Research Annual Meeting, April 2-6, 2011, Orlando, FL.  (Abstract #P4-03-02).

 

(107)   Cowan,R., Singh,G., and Ghert,M. The role of parathyroid hormone-related protein in giant cell tumour of bone.[Abstract] Bone 2011; 48: S48.

 

(106)   Trus,M., Lin,Y., Singh,G., and Minden,M.D. Combinations of epigenetic modifying agents accentuate retinoid-mediated gene expression over single agent therapies in acute myelogenous leukemia cells.  [Abstract] Blood 2010; 116: 1035.

 

(105)   Seidlitz,E., Sharma,M., and Singh,G. Intercellular communication in bone metastasis.[Abstract] Proceedings of the American Association for Cancer Research  2010; 2010. Poster presented at the American Association for Cancer Research Annual Meeting, April 17-21, 2010, Washington, D.C.

 

(104)   Sharma,M., Seidlitz,E., Saikali,Z., Ghert,M., and Singh,G. Characterization of glutamate transporters in cancer cells: Implications on normal bone formation.[Abstract]  Proceedings of the American Association for Cancer Research 2009; 2009: 1138. Poster presented at the American Association for Cancer Research Annual Meeting, April 18-22, 2009, Denver, Colorado.

 

(103)   Seidlitz,E., Sharma,M., Saikali,Z., Ghert,M., and Singh,G. Metastatic cancer cells release glutamate to disrupt bone turnover.[Abstract] Proceedings of the American Association for Cancer Research 2009; 2009: 3431. Poster presented at the American Association for Cancer Research Annual Meeting, April 18-22, 2009, Denver, Colorado.

 

(102)   Lemon,J., Armstrong,A.F., Parker,S., Appoh,F., Gavrila,A., Singh,G., and Valliant,J.F. Synthesis and in vitro screening of uPAR-targeting peptides for SPECT imaging of aggressive tumors.[Abstract] Proceedings of the International Society of Nuclear Medicine Meeting 2009. Presented at the International Society of Nuclear Medicine Annual Meeting, June 13-17, 2009, Toronto, Ontario.

 

(101)   Laflamme,P. and Singh,G. A targeted, high-throughput screening approach for inhibitors of reactive oxygen species in prostate cancer cells.[Abstract]Proceedings of the American Association for Cancer Research Annual Meeting 2009; 50: 371.

 

(100)   Hopmans,S., Cumming,A., Vukmirovic-Popovic,S., Singh,G., and Duivenvoorden,W. Effect of prostate-specific antigen on mouse bone metastasis from prostate cancer.[Abstract] Proceedings of the American Association for Cancer Research  2009; 2009: 286. Poster presented at the American Association for Cancer Research Annual Meeting, April 18-22, 2009, Denver, Colorado.

 

(99)   De Ciantis,P.D., Yashpal,K., Henry,J., and Singh,G. Prostate cancer induced bone metastasis and related nociceptive alterations in an animal model.[Abstract] Proceedings of the American Association for Cancer Research 2009; 2009: 2346. Poster presented at the American Association for Cancer Research Annual Meeting, April 18-22, 2009, Denver, Colorado.

 

(98)   Cowan,R., Mak,I., Singh,G., and Ghert,M. The pathophysiology of stromal cell-derived PTHrP in giant cell tumor of bone.[Abstract] Proceedings of the American Association for Cancer Research 2009; 2009: 1108. Poster presented at the American Association for Cancer Research Annual Meeting, April 18-22, 2009, Denver, Colorado.

 

(97)   Alqawi,O., Espiritu,M., and Singh,G. Metronomic ALA-PDT induces apoptosis through the inhibition of LT{beta}R.[Abstract] Proceedings of the American Association for Cancer Research 2009; 2009: 5146. Poster presented at the American Association for Cancer Research Annual Meeting, April 18-22, 2009, Denver, Colorado.

 

(96)   Alqawi,O., Espiritu,M., and Singh,G. Molecular mechanisms associated with ALA-PDT of brain tumor cells. [Abstract] 12th World Congress of the International-Photodynamic-Association (IPA) on Photodynamic Therapy - Back to the Future 2009.

 

(95)   Sharma,R., Duivenvoorden,W., and Singh,G. RANKL/OPG expression ratio in prostate cancer cell lines with varying bone metastatic potential.[Abstract] Proceedings of the American Association for Cancer Research 2008; 2008: 4087. Poster presented at the American Association for Cancer Research Annual Meeting, April 12-16, 2008, San Diego, California.

 

(94)   Pinthus,J.H., Lin,H., Bryskin,I., Kleinmann,N., Wilson,B., and Singh,G. Inter-related effects of androgens, fatty acids and oxidative stress in prostate cancer - A mechanistic support for prevention strategies.[Abstract] Journal of Urology 2008; 179: 42.

 

(93)   Pinthus,J., Daya,D., Srigley,J., Singh,G., Kleinmann,N., and Fridman,E. Construction of tissue micro array from prostate needle biopsies using vertical clustering re-arrangement technique.[Abstract] Journal of Clinical Oncology 2008; 26.

 

(92)   Ooi,W., Broom,R., Kahn,H., Christakis,M., Popovic,S., Kalina,M., Chesney,A., Singh,G., and Clemons,M. Exploration of the mechanisms of bone metastasis (BM) growth and resistance to bisphosphonate (BP) therapy in patients with metastatic breast cancer (MBC).[Abstract] Clinical & Experimental Metastasis 2008; 25: 51-52.

 

(91)   Lin,H., Laflamme,P., Bryskin,I., Wilson,B., Singh,G., and Pinthus,J. The effect of androgens on fatty acid oxidation in prostate cancer cells.[Abstract]Proceedings of the American Association for Cancer Research 2008; 2008: 474. Poster presented at the American Association for Cancer Research Annual Meeting, April 12-16, 2008, San Diego, California.

 

(90)   Kleinmann,N., Kapoor,A., Tisdale,B., Chatterjee,S., Lu,J., Singh,G., Hotte,S., and Pinthus,J. Lower plasma adiponectin levels are associated with larger tumor size and metastasis in clear cell carcinoma of the kidney.[Abstract] Journal of Clinical Oncology 2008; 26.

 

(89)   Fridman,E., Daya,D., Singh,G., Pinthus,J., and Srigley,J. Construction of tissue micro array from prostate needle biopsies using vertical clustering re-arrangement technique.[Abstract] Histopathology 2008; 53: 274-275.

 

(88)   De Ciantis,P.D., Henry,J.L., and Singh,G. Electrophysiological mapping of pain induced by bone metastasis.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 2008; 49: 872.

 

(87)   Cutz,J.C., Tsakiridis,T., Wright,J., Hirte,H., Singh,G., and Sao,M.S. Immunohistochemistry for phosphorylated EGF receptor predicts survival and phosphorylated ERK predicts tumor response to chemoradiotherapy in unresectable, locally advanced non-small cell lung cancer patients.[Abstract]Modern Pathology 2008; 21: 339A.

 

(86)   Tsakiridis,T., Wright,J., Cutz,J.C., and Singh,G. Plasma membrane and cytoplasmic activated EGF receptor predicts survival and cytoplasmic activated Erk predicts tumour response in locally advanced NSCLC patients treated with chemo-radiotherapy.[Abstract] Radiotherapy and Oncology2007; 84: S57.

 

(85)   Seidlitz,E., Kalina,M., Moore,C., Vukmirovic-Popovic,S., Duivenvoorden,W., and Singh,G. Spinal astroglial activation in bone metastasis pain is sensitive to systemic therapy.[Abstract] Proceedings of the American Association for Cancer Research 2007; 2007: 2223. Poster presented at the American Association for Cancer Research Annual Meeting, April 14-18, 2007, Los Angeles, California.

 

(84)   Hamelinck,D. and Singh,G. Role of uncoupling protein 2 in ovarian carcinoma.[Abstract] Proceedings of the American Association for Cancer Research 2007; 2007: 1064. Poster presented at the American Association for Cancer Research Annual Meeting, April 14-18, 2007, Los Angeles, California.

 

(83)   Eglence,A., McDuffee,L., Colterjohn,N., and Singh,G. In vitro analysis of human femoral cancellous bone as a viable source of osteoprogenitor cells and the effects of bone morphogenetic protein 2 and doxycycline on their differentiation into bone forming colonies.[Abstract] Bone 2007; 40: S167.

 

(82)   Duivenvoorden,W., Vukmirovic-Popovic,S., Kalina,M., Seidlitz,E., and Singh,G. Effect of zoledronic acid and doxycycline on tumor burden in a mouse bone metastasis model of human breast cancer.[Abstract] Proceedings of the American Association for Cancer Research 2007; 2007: 2194. Poster presented at the American Association for Cancer Research Annual Meeting, April 14-18, 2007, Los Angeles, California.

 

(81)   Cowan,R., Mak,I., Singh,G., and Ghert,M. Type I collagenase expression and activity in the osteoblastic stromal cells of giant cell tumor of bone.[Abstract] Proceedings of the American Association for Cancer Research 2007; 2007: 570. Poster presented at the American Association for Cancer Research Annual Meeting, April 14-18, 2007, Los Angeles, California.

 

(80)   Alqawi,O., Espiritu,M., Kerrigan,T., and Singh,G. Molecular mechanisms associated with ALA-PDT of brain tumor cells.[Abstract] Proceedings of the American Association for Cancer Research 2007; 2007: 4059. Poster presented at the American Association for Cancer Research Annual Meeting, April 14-18, 2007, Los Angeles, California.

 

(79)   Seidlitz,E., Kalina,M., and Singh,G. Spinal astrogliosis in an animal model of cancer-induced bone pain.[Abstract] Proceedings of the American Association for Cancer Research 2006; 2006: 236. Poster presented at the American Association for Cancer Research Annual Meeting, April 1-5, 2006, Washington, D.C.

 

(78)   Saikali,Z., Setya,H., Su,S., and Singh,G. Downregulation of galectin-1 in androgen-independent prostate cancer cells leads to impairment of survival and reduction in invasive capacity.[Abstract] Proceedings of the American Association for Cancer Research 2006; 2006: 807. Poster presented at the American Association for Cancer Research Annual Meeting, April 1-5, 2006, Washington, D.C.

 

(77)   Ooi,W.S., Gainford,C., Kahn,H., Kalina,M., Popovic,S., Singh,G., and Clemons,M. Why do patients with metastatic breast cancer (MBC) continue to have bone destruction despite bisphosphonate (BP) use? A pathologic review.[Abstract] Bone 2006; 38: S81.

 

(76)   Giles,E.D. and Singh,G. Role of IGFBP-3 in the proliferation of MDA-MB-231 breast carcinoma cells in bone metastasis.  [Abstract] Proceedings of the American Association for Cancer Research 2006; 2006: 71. Poster presented at the American Association for Cancer Research Annual Meeting, April 1-5, 2006, Washington, D.C.

 

(75)   Foroodi,F. and Singh,G. Treatment of breast cancer cells with combination therapy.[Abstract] Proceedings of the American Association for Cancer Research  2006; 2006: 1279. Poster presented at the American Association for Cancer Research Annual Meeting, April 1-5, 2006, Washington, D.C. 

 

(74)   Elavathil,L., Howatt,N., Hirte,H., Singh,G., Zanke,B., Kodeeswaran,S., Mishra,A., and Lytwyn,A. Ontario tumour bank initiative at Hamilton Health Sciences and the Juravinski Cancer Centre.[Abstract] Modern Pathology 2006; 19: 52.

 

(73)   Tsakiridis,T., Wright,J., Vincic,L., Junejo,M., Tsiani,E., Aljamad,H., Sur,R., Okawara,G., and Singh,G. p38 MAPK, Erk and Akt expression and activation in NSCLC tumors; Subcellular distribution and radiographic response to radiotherapy.[Abstract] Lung Cancer 2005; 49: S148.

 

(72)   Tsakiridis,T., Tsiani,E., Wright,J., Singh,G., Aljamad,H., Vincic,L., Sur,R., and Okawara,G. Activation of tyrosine kinase receptors and intracellular signal mediators in NSCLC tumors.[Abstract] Lung Cancer 2005; 49: S148.

 

(71)   Marra,S.A., Wilson,L.A., and Singh,G. Mitochondria-to-nucleus crosstalk mediated by Ets-1 in ovarian carcinoma cells.  [Abstract] Proceedings of the American Association for Cancer Research 2005; 2005: 1085. Poster presented at the American Association for Cancer Research Annual Meeting, April 16-20, 2005, Anaheim, California.

 

(70)   Hons,I.M. and Singh,G. Role of K-ATP channel activation on measures of mitochondrial function in cancer cells.[Abstract] Proceedings of the American Association for Cancer Research 2005; 2005: 194. Poster presented at the American Association for Cancer Research Annual Meeting, April 16-20, 2005, Anaheim, California.

 

(69)   Hiltz,A.C. and Singh,G. Examining the role of increased S100A4 expression in advanced prostate cancer using the LNCaP/CL-1 cell model.[Abstract]Proceedings of the American Association for Cancer Research 2005; 2005: 71. Poster presented at the American Association for Cancer Research Annual Meeting, April 16-20, 2005, Anaheim, California.

 

(68)   Dhesy-Thind,S.K., Julian,J., Tozer,R., Ellis,P., Arnold,A., Singh,G., and Levine,M. The effect of doxycycline on bone turnover and tumor markers in breast cancer (BC) patients with skeletal metastases.[Abstract] ASCO Meeting Abstracts 2005; 23: 3198.

 

(67)   Alqawi,O., Moghaddas,M., and Singh,G. The effect of geldanamycin on HIF-1 alpha mediated angiogenesis and invasion in prostate cancer cells DU145.[Abstract] Proceedings of the American Association for Cancer Research 2005; 2005: 265. Poster presented at the American Association for Cancer Research Annual Meeting, April 16-20, 2005, Anaheim, California.

 

(66)   Wilson,L., Gemin,A., Espiritu,R., and Singh,G. ARE mediated regulation of the transcription factor ETS-1.[Abstract] Free Radical Biology and Medicine 2004; 37: S74.

 

(65)   Wajstaub,S., Wright,J., Cleve,R., Chen,V., Singh,G., Hodson,I., Sathya,J., Sagar,S., and Browman,G. A study examining epidermal growth factor receptor, p53, and Bcl-2 expression in patients with locally advanced squamous cell carcinoma of the head and neck treated with concomitant chemoradiotherapy.[Abstract] Lung Cancer 2004; 46: S82-S83.

 

(64)   Van Lieshout,T.L. and Singh,G. The role of thioredoxin in prostate cancer cells under normoxic and hypoxic conditions.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 2004; 45: 1009.

 

(63)   Tsakiridis,T., Wright,J., Tsiani,E., Kalina,M., Singh,G., Vincic,L., and Hirte,H. Mitogen-activated protein kinase (MAPK) expression and activation in non-small cell lung cancer (NSCLC): Investigating their prognostic significance and role in radiation responses. [Abstract] Radiotherapy and Oncology2004; 72: S40-S41.

 

(62)   Setya,H.C., Fiebig,A., Singh,G., and Persad,S. Potential molecular mechanisms of insulin like growth factor-1 (IGF-1)/insulin like growth factor-1 receptor (IGF-1R) interaction in prostate cancer invasion.[Abstract] Proceedings of the American Association for Cancer Research 2004; 2004: 1160. Poster presented at the American Association for Cancer Research Annual Meeting, April 16-20, 2005, Anaheim, California.

 

(61)   Seidlitz,E., Su,S., Kalina,M., and Singh,G. Treatment of bone metastasis with a combination of doxycycline and zoledronate.[Abstract] Journal of Bone & Mineral Research 2004; 19: 1596-1597. Poster #89 presented at IVth International Conference on Cancer-Induced Bone Diseases, San Antonio, Texas, December 7-9, 2003.

 

(60)   Lacroix,S., Stanisz,J., Smolen,K., Wong,D., Richardson,M., and Singh,G. Fibrin(ogen) stimulates breast, ovarian, and prostate cancer cell line invasiveness on the chick chorioallantoic membrane.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 2004; 45: 418.

 

(59)   Jandu,N., Richardson,M., Singh,G., Southward,S.M., Hirte,H., and Hatton,M.W.C. Fibrinolytic profile and fibrin(ogen) degradation products (FDPs) in human ovarian cancer ascites fluid. [Abstract] FASEB J. 2004; 18: A196.

 

(58)   Gemin,A. and Singh,G. Retention of mitochondrial phenotypic properties during the transference of mtDNA from neoplastic cells.[Abstract]Proceedings of the American Association for Cancer Research 2004; 2004: 178. Poster presented at the American Association for Cancer Research Annual Meeting, Mar. 27-31, 2004, Orlando, Florida.

 

(57)   Chowdhury,S.K. and Singh,G. Role of mitochondrial glycerophosphate dehydrogenase (mGPDH) in prostate cancer cells.[Abstract] Proceedings of the American Association for Cancer Research 2004; 2004: 177. Poster presented at the American Association for Cancer Research Annual Meeting, Mar. 27-31, 2004, Orlando, Florida.

 

(56)   Bidaisee,L.A., Gupta,R.S., and Singh,G. Effect of testosterone on the mitochondrial aspartate aminotransferase in prostate cancer cell lines.[Abstract]Proceedings of the American Association for Cancer Research 2004; 2004: 446. Poster presented at the American Association for Cancer Research Annual Meeting, Mar. 27-31, 2004, Orlando, Florida.

 

(55)   Wilson,L., Yamamoto,H., and Singh,G. Ets-1: A target of mitochondrial signaling via reactive oxygen species.[Abstract] Free Radical Biology and Medicine 2003; 35: S76.

 

(54)   Boroojeni,P.K., Arakelian,A., Singh,G., and Rabbani,S.A. Herceptin can block the development of skeletal metastases and hypercalcemia of malignancy in a xenograft model of human breast cancer.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting2003; 44: 1232-1233.

 

(53)   Su,S. and Singh,G. Role of MMP-1 in osteolytic degradation by MDA-MB-231 cells.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 2002; 43: 537.

 

(52)   Preston,T.J. and Singh,G. JNK1 activity modulates the growth arrest response of ovarian adenocarcinoma cells to scavenging of extracellular hydrogen peroxide.[Abstract]  Proceedings of the American Association for Cancer Research Annual Meeting 2002; 43: 866.

 

(51)   Giles,E.D., Hirte,H., and Singh,G. Effect of the bone microenvironment on gene expression in breast carcinoma (MDA-MB-231) cells.[Abstract]Proceedings of the American Association for Cancer Research Annual Meeting 2002; 43: 900-901.

 

(50)   Duivenvoorden,W.C., Popovic,S.V., Lhotak,S., Seidlitz,E., and Singh,G. Doxycycline decreases tumor burden in a bone metastasis model of human breast cancer.[Abstract] Proceedings of the American Association for Cancer Research 2002; 2002: 317. Poster presented at the American Association for Cancer Research Annual Meeting, April 6-10, 2002, San Francisco, California.

 

(49)   Wilson,L., Sakata,K., and Singh,G. The transcription factor Ets-1 functions in the regulation of mitochondria.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 2001; 42: 648.

 

(48)   Wang,H.P., Hanlon,J.G., Lhotak,S., Espiritu,M., Rainbow,A.J., and Singh,G. Upregulation of heat shock protein 27 plays a critical role in the resistance of HT29 cells to singlet oxygen-mediated photooxidation.[Abstract] Free Radical Biology and Medicine 2001; 31: S142.

 

(47)   Sakata,K., Barrett,J., Tozer,R.G., and Singh,G. Role of PEA3 in prostate cancer.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 2001; 42: 658.

 

(46)   Hanlon,J.G., Austin,R., Rainbow,A., and Singh,G. Transfection with GRP78 causes cellular resistance to Photofrin(R) mediated photodynamic therapy.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 2001; 42: 932.

 

(45)   Barrett,J.M., Puglia,M.A., Sakata,K., Tozer,R.G., and Singh,G. Modulation of Ets transcription factor target gene expression in breast cancer cells.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 2001; 42: 656.

 

(44)   Abadi,A. and Singh,G. Mitochondrial permeability transition in acquired resistance to cisplatin.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 2001; 42: 425.

 

(43)   Shen,X.Y., Espiritu,M.B., Rainbow,A.J., and Singh,G. Increased Nip3 expression in photodynamic therapy resistant variants of HT29.[Abstract]Proceedings of the American Association for Cancer Research Annual Meeting 2000;  786.

 

(42)   Richardson,M., Hirte,H.W., Seidlitz,E., Lawrance,A., and Singh,G. Ascites fluid derived from human ovarian carcinoma induces epithelial proliferation and increases vascular permeability in the chick chorioallantoic membrane.[Abstract] Proceedings of the American Association for Cancer Research2000; 2000: 66. Poster presented at the American Association for Cancer Research Annual Meeting, April 1-5, 2000, San Francisco, California.

 

(41)   Preston,T.J. and Singh,G. Scavenging of extracellular H2O2 inhibits the proliferation of HER-2/Neu-transformed rat fibroblasts through multiple signalling pathways.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 2000;  789.

 

(40)   Lhotak,S., Elavathil,L., Duivenvoorden,W., Hirte,H., Daya,D., and Singh,G. Osteoclasts and tumor cells exhibit a different morphology of bone resorption pits and distinct matrix metalloproteinase profiles in bone metastasis of human breast carcinoma.[Abstract] Cancer 2000; 88: 3091-3092.

 

(39)   Lee,F.S.H., Su,S., Duivenvoorden,W.C., Hirte,H.W., and Singh,G. Doxycycline decreased prostate cancer-mediated calvarial bone resorption.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 2000;  137.

 

(38)   Richardson,M., Hirte,H., Seidlitz,E., Lawrance,A., and Singh,G. Ascites fluid induces epithelial proliferation and increases vascular permeability in the chorioallantoic membrane.[Abstract] Prostaglandins and Other Lipid Mediators 1999; 59: 175.

 

(37)   Preston,T. and Singh,G. Endogenous cellular H2O2 production regulates the HER-2/Neu signaling pathway.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1999; 40: 375.

 

(36)   Duivenvoorden,W., Hirte,H., and Singh,G. Human bone-metastatic cancer cells induce matrix metalloproteinase expression and activity in fibroblasts and osteoblast-like cells.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1999; 40: 461-462.

 

(35)   Duivenvoorden,W., Fourie,O., Hirte,H., and Singh,G. Tetracyclines induce cytotoxicity and inhibition of matrix metalloproteinase in human bone-metastasizing cancer cells.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1998; 39: 300-301.

 

(34)   Adams,K., Rainbow,R., Wilson,B., and Singh,G. Photodynamic therapy induces expression of the mitochondrial heat shock protein (Hsp60) in a photofrin-induced photodynamic therapy resistant cell variant.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1998; 39: 280.

 

(33)   Shaw,T. and Singh,G. Peripheral benzodiazepine receptor as a target for cancer treatment.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1997; 38: 602.

 

(32)   Roy,D., Singh,G., Wilson,B., and Rainbow,A. PDT treatment of murine fibrosarcoma cells results in enhanced repair of a UV-damaged reporter gene.[Abstract] Photochemistry and Photobiology 1997; 65: 83S.

 

(31)   Duivenvoorden,W. and Singh,G. Expression of matrix metalloproteinase-1 is induced by transforming growth factor-beta-1 in metastatic human breast cancer MDA-MB-231 cells.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1997; 38: 409.

 

(30)   Austin,R.C., Sood,S.K., Outinen,P.A., Dorward,A.M., Singh,G., Shaughnessy,S.G., and Weitz,J.I. Homocysteine alters mitochondrial gene expression, function and structure.[Abstract] Blood 1997; 90: 1358.

 

(29)   Sanchez-Sweatman,O., Khokha,R., Kruger,A., Lee,J., Singh,G., and Orr,F. Evidence for tumor-mediated osteolysis in experimental bone metastasis.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1996; 37: 88.

 

(28)   Roy,D., Singh,G., Wilson,B., and Rainbow,A. Response of murine fibrosarcoma cells to photodynamic therapy mediated by the ruthenium phthalocyanine, JM2929.[Abstract] Photochemistry and Photobiology 1996; 63: 98S.

 

(27)   Nefedova,E. and Singh,G. Delay in G2 arrest in human ovarian carcinoma cells (2008) following cisplatin treatment.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1996; 37: 321.

 

(26)   Moorehead,R. and Singh,G. Elevated expression of the c-fos gene can contribute to cisplatin resistance. [Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1996; 37: 320-321.

 

(25)   Dorward,A. and Singh,G. N-acetyl-L-cysteine (NAC) alters cell cycle progression in ovarian cancer cells of epithelial origin.[Abstract] FASEB J. 1996; 10: A1288.

 

(24)   Caney,C., Lukka,H., Singh,G., and Rainbow,A. Pretreatment of a human squamous cell line with low-dose cisplatin leads to increased survival following gamma-irradiation.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1996; 37: 613-614.

 

(23)   Adams,K.E., Espiritu,M., Wilson,B.C., and Singh,G. Photodynamic therapy-resistant cells maintain their resistance in vivo.[Abstract] Photochemistry and Photobiology 1996; 63: 98S.

 

(22)   Sweet,S. and Singh,G. Changes in mitochondrial mass and membrane potential during the cell cycle of HL-60 cells.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1995; 36: 28.

 

(21)   Srivastava,A., Leber,B., Andrews,D., and Singh,G. The role of BCL-2 expression in mediating cisplatinum resistance.[Abstract] Blood 1995; 86: 781A.

 

(20)   Srivastava,A. and Singh,G. Cisplatin resistance mediated by bcl-2.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1995; 36: 18.

 

(19)   Sanchez-Sweatman,O., Khokha,R., Singh,G., and Orr,F. Mechanisms of bone degradation by human cancer cell lines obtained from bone metastases.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1995; 36: 85.

 

(18)   Kostenuik,P.J., Orr,F., and Singh,G. Transforming growth factor-beta stimulates the integrin-mediated adhesion of prostatic carcinoma cells to bone cell matrix.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1995; 36: 86.

 

(17)   Kostenuik,P.J., Orr,F., and Singh,G. TGF-beta stimulates the alpha-2-beta-1 integrin-mediated adhesion of PC-3 prostatic carcinoma cells to type I collagen.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1995; 36: 62.

 

(16)   Dorward,A. and Singh,G. Alterations in cellular glutathione metabolism in cisplatin resistant human ovarian cancer cells: Correlation to changes in mitochondrial membrane potential.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1995; 36: 313.

 

(15)   DiProspero,L., Singh,G., Wilson,B., and Rainbow,A. Cross-sensitivity to photodynamic therapy and UV light in a Chinese hamster ovary cell mutant deficient in folylpolyglutamate synthetase.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1995; 36: 609.

 

(14)   Sweet,S. and Singh,G. Alteration of cell cycle with mitochondrial-specific agents: Implications in cancer chemotherapy.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1994; 35: 25.

 

(13)   Sanchez-Sweatman,O., Khokha,R., Singh,G., and Orr,F. Cancer cells metastatic to bone directly degrade bone matrix: Potential role of matrix metalloproteinases.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1994; 35: 71.

 

(12)   Sanchez-Sweatman,O., Khokha,R., Singh,G., and Orr,F. Bone metastasis: potential role of tumour-derived matrix metalloproteinases in bone matrix degradation.[Abstract] Clinical and Investigative Medicine 1994; 17: B104.

 

(11)   Moorehead,R., Rainbow,A., and Singh,G. Effect of mitochondrial alterations on the repair of cisplatin-induced DNA damage.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1994; 35: 438.

 

(10)   Kostenuik,P., Singh,G., and Orr,F. Preferential adhesion of PC-3 prostate cancer cells to osteoblast like matrix.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1994; 35: 56.

 

(9)   Dorward,A.M., Moorehead,R.A., Sweet,S.M., and Singh,G. Tumour Mitochondria As A Target for Cancer Chemotherapy.[Abstract] Proceedings of the Xvi International Cancer Congress - Free Papers and Posters, Tomes 1-4 1994;  2859-2863.

 

(8)   Dorward,A. and Singh,G. Energetic characteristics of a human ovarian cell line resistant to cisplatin: Sensitivity to mitochondrial inhibition.[Abstract]Proceedings of the American Association for Cancer Research Annual Meeting 1994; 35: 10.

 

(7)   Armstrong,S., Porter,L., and Singh,G. Tamoxifen does not potentiate the effect of cisplatin in human ovarian cancer cells in vitro.[Abstract]Proceedings of the American Association for Cancer Research Annual Meeting 1994; 35: 437.

 

(6)   Sharkey,S., Wilson,B., and Singh,G. Cellular characterization of photofrin mediated photodynamic therapy resistant cells.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1993; 34: 358.

 

(5)   Sanchez-Sweatman,O., Soares,F., Whaley,M., Khokha,R., Singh,G., and Orr,F. Modulation of human cancer cell matrix metalloproteinases by exogenous factors.[Abstract] Proceedings of the American Association for Cancer Research Annual Meeting 1993; 34: 82.

 

(4)   McKay,M., Macarios,D., Molloy,D.W., and Singh,G. Relationship between mitochondrial-DNA and Alzheimer's disease.[Abstract] FASEB J. 1993; 7: A627.

 

(3)   Kostenuik,P., Singh,G., Suyama,K., and Orr,F.W. Bone remodeling rate correlates with bone metastasis and tumor cell growth in-vivo.[Abstract]Faseb Journal  1992; 6: A1948.

 

(2)   Orr,F.W., Millar-Book,W., and Singh,G. Chemotactic and growth factor activity of bone-derived TGF-beta for bone-metastasizing rat Walker 256 carcinosarcoma cells.[Abstract] Faseb Journal 1990; 4: A1134.

 

(1)   Macdonald,I.A., Singh,G., Markus,I.S., and Tan,M. Suppression of human fecal NAD-dependent 7-alpha hydroxy steroid dehydrogenase by a short-term low cholesterol diet.[Abstract] Canadian Federation of Biological Societies Proceedings 1979; 22: 105.